Analgesic Effectiveness of Three Different Doses of a New Formulation of Lamaline in a Model of Painful Knee (Gonarthrosis)

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to assess the analgesic effectiveness and safety of three different doses of a new formulation of Lamaline® versus Dafalgan® Codeine after 10 days administration in subjects with painful gonarthrosis

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Solvay Pharmaceuticals
• Treatments: Analgesics; Codeine

Criteria

Inclusion Criteria:

• History of knee (unilateral or bilateral) osteoarthritis for at least 6 months

• Pain intensity assessed by Visual Analogue Scale ≥ 40 mm

• Partial functional disability assessed by Lequesne index ≥4 and < than 12

Exclusion Criteria:

• Patient unable to interrupt his/her NSAIDs to participate in the clinical study