Overview

Analgesic Effect of Oxytocin Receptor Modulation

Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
Carbetocin is a synthetic analogue of the hormone Oxytocin and is routinely used in obstetric anesthesiology to control uterine bleeding after cesarean section. As an incidental finding, women who received carbetocin had less pain after cesarean section than women who had received Oxytocin. Carbetocin may therefore have an analgesic effect. The present study examines this analgesic effect using different sensory tests, e.g. pressure, heat, cold and electrical pain before and after administration of carbetocin in healthy male volunteers. Any changes in these sensory tests might be indicative of an analgesic property of carbetocin.
Phase:
N/A
Details
Lead Sponsor:
University Hospital Inselspital, Berne
Treatments:
Analgesics
Carbetocin
Oxytocin