Analgesic Effect of Ketamine Vs Ketamine Magnesium Infusion and Their Effect on Postoperative Morphine Consumption

• Status: Completed
• Trial end date: 2022-05-15
• Target enrollment: 0
• Participant gender: All

Summary

Ketamine and magnesium-ketamine are two analgesics that are being studied for use as adjuvants. They were shown to have anaesthetic and analgesic properties, and as a consequence of this finding, it has been postulated that they may have a role in minimising the requirement for analgesic drugs during the postoperative period. The major objective of the research was to examine the pain-relieving effects of ketamine vs ketamine magnesium infusion, as well as their influence on postoperative morphine consumption following nephrectomy; the secondary goal is to assess hemodynamic effects and pain severity.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Egymedicalpedia
• Treatments: Ketamine; Morphine

Criteria

Inclusion Criteria:

• Patients with elective nephrectomy

Exclusion Criteria:

• Pregnant women

• Cases with severe chronic disease as liver cell failures, CHF

• cases with allergies to ketamine and magnesium sulphate

• cases with a history of current regular use of (analgesic, anticonvulsant, antidepressant)

• chronic pain.

• mental illness.