Analgesic Effect of Beta 2-mimetics in the Treatment of Neuropathic Pain
Status:
Terminated
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
Neuropathic pain is due to a lesion or disease affecting the nervous system. Antidepressants
(ADs) are recommended as the first line treatment. In a murine model, the investigators
evidenced that antidepressants antiallodynic action is mediated through β2-adrenergic
receptor stimulation and that β-mimetics display the same effect. These data support the idea
that β-mimetics could offer a therapeutic alternative to ADs for neuropathic pain treatment.
This study will aim at assessing the effects of terbutaline on neuropathic pain symptoms.