Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific Inhibitor

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Acute pain is the result of activating nociceptive pathways in both the peripheral and central nervous system. The origin of most acute pain from surgical stimulation is the mechanical trauma of the local tissue and the subsequent acute inflammatory response.

No studies have investigated the combined use of anti-inflammatory analgesics with spinal anaesthesia/analgesia for pre, intra and postoperative multimodal pain protection in patients undergoing day-case IHR. The aim of the investigators study is therefore to assess the efficacy of preoperative combined administration of etoricoxib and standard spinal anaesthesia in the reduction of postoperative pain following IHR.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bnai Zion Medical Center
• Treatments: Anesthetics; Etoricoxib

Criteria

Inclusion Criteria:

• American Society Anesthesiology Class I and II

Exclusion Criteria:

• Under treatment with Non Steroid Antinflammatory Drug

• Under Opioid treatment

• Peptic ulcer

• Liver insufficiency

• Renal insufficiency

• Asthma

• Cardiovascular disease