Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific Inhibitor
Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
Acute pain is the result of activating nociceptive pathways in both the peripheral and
central nervous system. The origin of most acute pain from surgical stimulation is the
mechanical trauma of the local tissue and the subsequent acute inflammatory response.
No studies have investigated the combined use of anti-inflammatory analgesics with spinal
anaesthesia/analgesia for pre, intra and postoperative multimodal pain protection in patients
undergoing day-case IHR. The aim of the investigators study is therefore to assess the
efficacy of preoperative combined administration of etoricoxib and standard spinal
anaesthesia in the reduction of postoperative pain following IHR.