Anabolic Steroid and Propranolol in Paediatric Burn

• Status: Recruiting
• Trial end date: 2023-09-28
• Target enrollment: 0
• Participant gender: All

Summary

propranolol and anabolic steroids have a role in pediatric burn patients and their combined effects are to be studied here. They decrease the catabolic response to burn trauma and minimize the duration of growth arrest hence improving the outcome

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: King Edward Medical University
• Treatments: Nandrolone; Nandrolone Decanoate; Nandrolone phenpropionate; Propranolol

Criteria

Inclusion Criteria:

• Patients presenting within 48 hours of burn

• more than 20% and less than 40 %of TBSA burn (measured via modified rule of nine for pediatric burn according to age)

• age 2-12 years (as safety of anabolic steroids is not established in <2years of age)

• Scald and flame burn

Exclusion Criteria:

• Diabetics (diagnosed before hospital admission)

• Renal disease (diagnosed before hospital admission)

• Asthmatics (on medication previously)

• Cardiac anomalies (previously diagnosed)

• Patients requiring cardiac support (norepinephrine, dobutamine at any dose and dopamine >7ug/kg).

• All 4 limbs burnt