An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia
Status:
Completed
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
This study is being carried out to see if the study medication, rosuvastatin, is effective in
treating familial hypercholesterolaemia in children and adolescents, and to determine the
long term (over 2 years) safety, tolerability and efficacy of the study medication in these
patients.
This study will also measure levels of drug in the blood and see how well it is tolerated.
This is known as pharmacokinetic (PK) analysis.
At baseline only a small number of patients will participate in a single dose PK phase over
24 hours.
In order to see if this medication works, a control group of healthy siblings will help the
researchers to compare certain results.