An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications.
Status:
Completed
Trial end date:
2007-10-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to evaluate the effectiveness, safety, and tolerability of metformin
treatment in children and adolescents suffering from weight gain secondary to use of atypical
antipsychotic medications. In this 12 week, open-label study we will investigate metformin's
effects on weight control and/or weight loss. We hypothesize that metformin would prevent
further weight gain or lead to weight loss, resulting in amelioration of one of the most
significant side effects of atypical antipsychotic use.