Overview

An Open-label Study in Healthy Participants to Evaluate AZD0780 as an Object or Precipitant of CYP3A4-mediated Drug-drug Interactions

Status:
COMPLETED

Trial end date:
2025-02-17

Target enrollment:

Participant gender:

Summary

An open-label, fixed sequence study in healthy participants to assess the pharmacokinetics of AZD0780 when administered alone and in combination with itraconazole and carbamazepine, and to assess the pharmacokinetics of midazolam and ethinyl estradiol/levonorgestrel (EE and LNG) when administered alone and in combination with AZD0780.

Phase:

PHASE1

Details

Lead Sponsor:

AstraZeneca

Treatments:

Carbamazepine
Ethinyl Estradiol-Norgestrel Combination
Itraconazole
Midazolam