Overview

An Open-label Drug-Drug Interaction Study to Evaluate the Effect of BCX7353 on Cytochrome P450 Enzyme Activity Using Probe Substrates

Status:
Completed

Trial end date:
2016-06-01

Target enrollment:

Participant gender:

Summary

This is an open-label, single sequence study to evaluate the effect of BCX7353 on hepatic and intestinal cytochrome P450 enzymes using probe substrate drugs in healthy subjects. Pharmacokinetics of the probe substrate drugs will be measured prior to and following administration of multiple doses of BCX7353.

Phase:

Phase 1

Details

Lead Sponsor:

BioCryst Pharmaceuticals

Treatments:

Berotralstat