Overview

An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies

Status:
Terminated
Trial end date:
2019-02-27
Target enrollment:
Participant gender:
Summary
This was a study of INCB052793 given to patients with advanced malignancies that was to be conducted in three phases; Phase 1a (Monotherapy) and Phase 1b (Combination Therapy) and Phase 2 (Combination therapy of INCB052793 with azacitidine and itacitinib with azacitidine). Phase 1 had two parts; a dose escalation (Part 1) and an expansion (Part 2).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Incyte Corporation
Treatments:
Azacitidine
BB 1101
Bortezomib
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Gemcitabine
Lenalidomide
Paclitaxel
Pomalidomide