An Intervention to Examine the Effect of Vitamin D on Urine Protein Levels in Type 2 Diabetes
Status:
Unknown status
Trial end date:
2019-05-10
Target enrollment:
Participant gender:
Summary
Diabetic kidney disease (nephropathy) develops in nearly 40% of patients with type 2 diabetes
mellitus. Diabetic nephropathy is caused by damage to the small blood vessels in the kidneys
due to uncontrolled blood sugar levels, which mean that the kidneys become less effective at
filtering urine. This is associated with albuminuria (protein in the urine). Treatment with
some drugs reduces the loss of albumin through the urine and delays disease progression.
There is increasing evidence that vitamin D could also be important in management of diabetic
kidney disease. The aim of this study is to investigate the efficacy and safety of a combined
regimen of calcitriol (active vitamin D) and established drugs for diabetic kidney disease.