An Innovative Treatment for Fistula-in-ano in Crohn Disease : Local Micro Reinjection of Autologous Fat and SVF
Status:
Completed
Trial end date:
2018-02-01
Target enrollment:
Participant gender:
Summary
Crohn's disease is a chronic inflammation of all or part of the digestive tract, " from the
mouth to the anus ". .
Cell therapy is a new and promising approach for the treatment of inflammatory disease
including Crohn's disease and fistulas.
Adipose tissue seems to be an ideal source for cell therapy. This is a prospective, open,
non-comparative, single center, phase I-II clinical trial. It will involve 10 patients and
will be conducted over a period of 28 month.
This protocol is designed to evaluate, in patients with Crohn's disease and fistula-in-ano
refractory to conventional medical and surgical treatment, the safety and efficacy of local
microinjection of autologous adipose tissue and SVF from microaspirate .
The main objective is to assess tolerance and security. The secondary objective is to
evaluate the effectiveness of this technique