An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease
Status:
Terminated
Trial end date:
2004-11-01
Target enrollment:
Participant gender:
Summary
Although the serious form of West Nile Virus (WNV) disease, referred to as neuroinvasive
disease, is rare, it can result in permanent disabilities and occasionally death. For
patients who get this serious form of WNV disease, there are no approved specific treatment
options.
The purpose of this study is to test a new drug, AVI-4020 Injection, in patients who are
hospitalized with recent symptoms of this form of WNV disease. In this study, we will
determine if the AVI-4020 treatment is safe. This will be accomplished by reviewing the
results of laboratory tests and clinical signs and symptoms. Additionally, we will review the
patient data for signs that AVI-4020 is providing any beneficial effects against WNV
neuroinvasive disease.