An Evaluation of the Safety and Efficacy of Memantine in Patients With Acute Mania Associated With Bipolar I Disorder
Status:
Completed
Trial end date:
2005-11-01
Target enrollment:
Participant gender:
Summary
Bipolar disorder affects 2.4 million adults in the USA between the ages of 18-65 and has
considerable economic impact on our society. Bipolar mania accounts for 1 in 7 psychiatric
emergencies and is associated with significant morbidity and mortality. The purpose of the
study is to evaluate the safety and efficacy of open-label memantine in the acute management
of adults with bipolar I disorder hospitalized for mania.