An Efficacy and Tolerability Study of Topiramate in Participants With Migraine
Status:
Completed
Trial end date:
2008-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the adequacy (reasonably good) of topiramate
therapy (medicine or medical care given to a participant for a disease or condition) in
prevention of migraine (type of severe headache that occurs periodically and is often
associated with nausea, vomiting, and constipation or diarrhea) by comparing standard
titration (slow increase in drug dosage, guided by patient's responses) therapy to slow
titration therapy and slow titration therapy boosted by the concurrent use of propranolol in
participants with migraine with or without aura (having to do with the ear) for more than or
equal to 2 attacks per month.