Children with thalassemia may have high iron levels after receiving blood transfusions. These
high iron levels can have damaging effects on the body, especially the heart. Conventionally
only chelation therapy was given for prevention of iron buildup in the heart. However,
current research has shown that another drug, amlodipine, also helps to slow down the
deposition of iron in the heart. This study is designed to see if patients receiving
amlodipine along with their regular chelation therapy have a slower rate of iron buildup in
the heart when compared with patients who are receiving chelation only.