Overview

Amlodipine as add-on to Olmesartan in Hypertension

Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
0
Participant gender:
All
Summary
Test the efficacy and safety of the combination of olmesartan and amlodipine in hypertensive patients whose blood pressure is not adequately controlled with olmesartan alone.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Sankyo Pharma Gmbh
Treatments:
Amlodipine
Olmesartan
Olmesartan Medoxomil
Criteria
Inclusion Criteria:

- Mean sitting BP of greater than or equal to 140/90-115 mmHg and mean 24h dBP greater
than or equal to 80 mmHg with at least 30% of daytime readings greater than 85 mmHg
prior to randomization.

Exclusion Criteria:

- Secondary hypertension of any aetiology;

- Any serious disorders which may limit the ability to evaluate the efficacy or safety
of the test drug(s);

- History of myocardial infarction, unstable angina pectoris, percutaneous coronary
intervention, congestive heart failure, hypertensive encephalopathy, stroke or TIA
within the last 6 months.