Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension
Status:
Recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
A significant number of pregnancies are complicated by hypertensive disorders. Hypertension
often worsens in the postpartum period and many women need started on medications. Currently,
recommended medications for blood pressure management in pregnant and postpartum women are
limited, with labetalol and nifedipine ER being the most commonly used medications. While
these medications are both effective, they are not without limitations. Amlodipine is a
medication in the same class as nifedipine ER. It is a first-line antihypertensive in the
general population. It tends to have less side effects than nifedipine ER. It has not been
studied specifically in postpartum women. The purpose of this study is to determine if
amlodipine is noninferior to nifedipine ER in managing hypertension in the postpartum period.