Aminophylline in Bradyasystolic Cardiac Arrest

• Status: Completed
• Trial end date: 2004-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effect of aminophylline in patients with out-of-hospital bradyasystolic cardiac arrest.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vancouver General Hospital
• Collaborators: Heart and Stroke Foundation of Canada; Vancouver Coastal Health Research Institute
• Treatments: Aminophylline

Criteria

Inclusion Criteria:

• Cardiac arrest

• Bradyasystole either as the presenting rhythm or as a rhythm developing during the course of the resuscitation

• Endotracheally intubated and ventilated with 100% oxygen

• Intravenous (IV) access established

• Bradyasystolic without palpable pulses after 1 mg of epinephrine and 3 mg of atropine.

Exclusion Criteria:

• A do-not-resuscitate directive

• Pregnancy

• Evidence of hemorrhage, trauma or hypothermia as a cause of the cardiac arrest

• Renal dialysis

• Theophylline hypersensitivity

• Patients taking an oral theophylline product

• Resuscitations directed by a paramedic student under practicum supervision