Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve
Status:
Unknown status
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
Following acute inflammation of the optic nerve region, as commonly seen in multiple
sclerosis patients, the optic nerve often undergoes atrophy, thus representing permanent
damage. Data from animal studies suggest that amiloride may prevent this process. The aim of
this study is to assess a potential neuroprotective effect of amiloride in acute autoimmune
inflammation of the optic nerve region.
Phase:
Phase 2
Details
Lead Sponsor:
Medical University of Vienna
Treatments:
Amiloride Amiloride, hydrochlorothiazide drug combination Hydrochlorothiazide