Overview

Alternative Dosing And Prevention of Transfusions (ADAPT)

Status:
Recruiting
Trial end date:
2025-01-31
Target enrollment:
Participant gender:
Summary
ADAPT is a prospective cohort study at Jinja Regional Referral Hospital (JRRH) primarily to assess the effect of hydroxyurea on blood transfusion utilization and secondarily to determine the feasibility of PK-guided hydroxyurea dosing.
Phase:
Early Phase 1
Details
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Collaborator:
Jinja Regional Referral Hospital (JRRH), Sickle Cell Clinic, Jinja, Uganda
Treatments:
Hydroxyurea