Alternative Antibiotic Regime in the Treatment of GAgP
Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The objective of this randomized clinical study was to evaluate the effect of systemic
administration of moxifloxacin compared to amoxicillin plus metronidazole combined with
non-surgical treatment in patients with generalized aggressive periodontitis (GAgP) in
6-month follow-up.
A total of 40 systemically healthy patients with GAgP will evaluate in this randomized
clinical trial. Periodontal parameters (plaque index, gingival index, probing depth, bleeding
on probing, clinical attachment level) will be recorded at baseline, 1st, 3rd and 6th month.
Patients will receive either 400 mg moxifloxacin per os once daily or 500 mg metronidazole
and 500 mg amoxicillin per os three times daily for 7 days consecutively.
Phase:
Phase 4
Details
Lead Sponsor:
Kocaeli University
Treatments:
Amoxicillin Fluoroquinolones Metronidazole Moxifloxacin Norgestimate, ethinyl estradiol drug combination