Altering Bicarbonate Delivery During Hemodialysis to Affect Filtration of Indoxyl Sulfate
Status:
Withdrawn
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
This is a non randomized crossover trial investigating whether changing the pattern of
bicarbonate administration during hemodialysis will result in the more efficient filtration
of highly protein bound solutes. The experimental group will be dialyzed with low bicarbonate
dialysate for the first half of dialysis then switched over to normal bicarbonate dialysate
for the second half. The control group will be dialyzed entirely with normal bicarbonate
dialysate. The two groups will switch one week late and patients will serve as their own
matched controls for a completely standard dialysis and one that is split into two halves
with different bicarbonate concentrations.
Phase:
N/A
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health