Alteplase for Blood Flow Restoration in Hemodialysis Catheters
Status:
Terminated
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
We are investigating a new way of administering alteplase to remove clots from hemodialysis
catheters. Currently, alteplase is left to dwell inside the catheter between dialysis
treatments to dissolve the clot and restore blood flow through the catheter. We have
developed a new way to administer alteplase by advancing it to the tip of the catheter at
regular 10 minute intervals. We hypothesize that our new "push" protocol will dissolve clots
in hemodialysis catheters better and faster than the current dwell method.