Aloe Vera and Chlorhexidine Against Traumatic Oral Ulcers
Status:
Completed
Trial end date:
2018-01-01
Target enrollment:
Participant gender:
Summary
The development of gingivitis in patients during orthodontic treatment is widely known, with
the characteristic response of gingival inflammation and hyperplasia and traumatic rashes or
ulcerations of the oral mucosa derived from the treatment. The use of chemical agents such as
CHX, although it has proven to be useful in these patients, but has the disadvantage of
having side effects such as staining, even restricting its use during treatment.
The objective of this study was to determine the efficacy of Aloe vera gel at 80% compared to
0.12% Chlorhexidine gel to alleviate the effects derived from any orthodontic treatment, such
as gingival inflammation and hyperplasia and friction or ulcerations. of traumatic oral
mucosa-derived from treatment in patients after cementation with metal brackets in the two
arches. A total of 140 patients between the ages of 10 and 55 who were randomized and
assigned in the two study groups treated with Aloe vera gel versus the conventional
Chlorhexidine gel with a sample of 70 subjects in each group participated.
The index of gingival inflammation, plaque index, as well as the simplified hemorrhage index,
were evaluated.
Phase:
Phase 4
Details
Lead Sponsor:
University of Santiago de Compostela
Collaborators:
Alfonso X El Sabio University University of Alfonso X El Sabio
Treatments:
Anti-Infective Agents, Local Chlorhexidine Chlorhexidine gluconate