Aloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 Diabetics
Status:
Not yet recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
The objectives of the present study are to:
1. Compare the clinical efficacy of (50%) aloe vera versus (20%) thyme honey mouthwash on
management of xerostomia in diabetic patients by measuring the salivary flow rate as a
primary objective.
2. Asses the biochemical effect of aloe vera and thyme honey on the level of salivary
nitric oxide, xerostomia grade as well as patient quality of life as a secondary
objective.
Research question:
Which is better aloe vera or thyme honey in improving salivary flow rate in diabetic patients
suffering from xerostomia?
Patient Grouping and Randomization:
Patients with xerostomia will be randomly distributed into three groups using a
computer-generated randomization table. Allocation concealment will be achieved by a sealed
opaque envelope with a ratio of 1:1:1
Group 1 (Aloe Vera group)
Include (15) patient suffering from diabetes induced xerostomia that will receive aloe vera
as mouthwash
Group 2 (Thyme honey group):
Include (15) patient suffering from diabetes induced xerostomia that will receive thyme honey
mouthwash
Group 3 (Saline control group):
Include (15) patient suffering from diabetes induced xerostomia that will receive saline
mouthwash