Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors
Status:
Unknown status
Trial end date:
2015-05-01
Target enrollment:
Participant gender:
Summary
The study proposes the use of Fludarabine, Busulfan, Anti Thymocyte Globulin Rabbit (ATG) and
Total Body Irradiation as a preparative regimen before hematopoietic stem cell transplant
from unrelated donor peripheral blood stem cells (PBSC). The hypothesis states that the 100
day mortality after this type of transplant will be significantly below the accepted
standards, which is about 30% for unrelated donors.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Ann & Robert H Lurie Children's Hospital of Chicago