Allogeneic Natural Killer (NK) Cells in Patients With Advanced Metastatic Breast Cancer
Status:
Terminated
Trial end date:
2010-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Giving chemotherapy before a donor natural killer (NK) cell infusion helps stop
the growth of tumor cells. It also helps stop the patient's immune system from rejecting the
donor's cells. Giving NK cells from a related donor may kill the tumor cells.
PURPOSE: This study furthers the research of previous studies (MT2003-01 and MT2004-25) which
were to determine a specific preparatory regimen (cyclophosphamide and fludarabine) could
create an environment in which infused NK cells can grow and effectively treat patients with
relapsed AML. This study will test the previous regimen in patients with breast cancer.