Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes
Status:
Completed
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Although used primarily to treat malignant disorders of the blood, allogeneic stem
cell transplantation can also cure a variety of non-cancerous, inherited or acquired
disorders of the blood. Unfortunately, the conventional approach to allogeneic stem cell
transplantation is a risky procedure. For some non-cancerous conditions, the risks of this
procedure outweigh the potential benefits. This protocol is designed to test a new approach
to allogeneic stem cell transplantation. It is hoped that this approach will be better suited
for patients with non-cancerous blood and bone marrow disorders.