Overview

Allogeneic Hematopoietic Stem Cell Transplantation

Status:
Unknown status
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
To assess the engraftment of hematopoietic stem cells following reduced-intensity conditioning in children presenting with solid tumors or hematological malignancy by evaluating post-transplantation chimerism and hematological reconstitution. To study acute and/or chronic graft-versus-host reaction (incidence and severity) and immune reconstitution, post-transplantation To study the effectiveness of the protocol on tumor response. To study overall survival.
Phase:
Phase 2
Details
Lead Sponsor:
University Hospital, Clermont-Ferrand
Treatments:
Busulfan
Fludarabine
Fludarabine phosphate
Thymoglobulin