Metabolic acidosis recovers a wide range of diseases in which an oral alkalinization could be
useful. This therapeutic intervention has been said to increase extracellular volume leading
to rising blood pressure. No prospective data has been published in clinical routine. Here,
investigators propose to follow patients in which an oral alkalinization is indicated: blood
pressure, body weight, and a clinical evaluation of the extracellular compartment will be
performed at the beginning and during the follow-up of participants. The principal criterion
of evaluation will be the variation in the extracellular compartment.