Alimta® Plus Cisplatin & Paclitaxel Given Intraperitonelly; First Line Tx Stage III Ovarian Cancer
Status:
Completed
Trial end date:
2012-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Pemetrexed may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Drugs used in chemotherapy, such as cisplatin and paclitaxel, work in
different ways to stop the growth of tumor cells, either by killing the cells or by stopping
them from dividing. Giving pemetrexed together with cisplatin and paclitaxel and giving them
in different ways may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of intraperitoneal
pemetrexed when given together with intraperitoneal cisplatin and paclitaxel in treating
patients with stage III ovarian epithelial cancer, primary peritoneal cancer, or fallopian
tube cancer.