Alcohol and Cigarette Craving During Oxytocin Treatment
Status:
Recruiting
Trial end date:
2024-09-01
Target enrollment:
Participant gender:
Summary
This proposed research seeks to examine the behavioral and neural substrates of intranasal
oxytocin compared to placebo on alcohol cue-induced alcohol and cigarette craving smokers
with an alcohol use disorder (AUD). Non treatment-seeking smokers with an AUD will be
recruited to participate in a between-subjects, placebo-controlled, randomized pilot
functional magnetic resonance imaging (fMRI) study. Participants will undergo an fMRI scan in
conjunction with an alcohol-olfactory cue-reactivity task. Secondary assessments will include
alcohol and cigarette craving, alcohol and cigarette consumption, physiological measures
(heart rate and blood pressure) and mood measures.
Phase:
Phase 1
Details
Lead Sponsor:
Brown University
Collaborator:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)