Aggravated Airway Inflammation: Research on Genomics and Optimal Medical Care (AirGOs-medical)
Status:
Recruiting
Trial end date:
2027-03-31
Target enrollment:
Participant gender:
Summary
The study is performed as a randomized double-blinded prospective controlled trial. A total
of 72 adult Acetyl salicylic acid (ASA) -exacerbated respiratory disease (AERD) -patients
with uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) will be recruited. Those
negative to ASA-challenge test will not enter the Clinical Trial . All patients entering the
Clinical Trial, have undergone earlier ethmoidal surgery (partial/total) and have not gained
disease control. F-helicobacter antigen is tested and treatment is given if indicated. The
patients are recruited at the Helsinki University Hospital (HUH). The study will be monitored
by a professional monitor. Electronic CRF and paper/electronic patient questionnaires
provided by HUS will be used (eCRF and patient questionnairea, Granitics).