Increased accessibility to cannabis and its primary psychoactive constituent THC has raised
public health concerns. One major concern surrounds the potential risks associated with acute
THC intoxication and who might be most at risk. A second major concern is the need to develop
sensitive measures that can detect THC intoxication after recent use and enable robust
comparisons of intoxication to determine sources of risk. One potential source of risk is
age, specifically during the period of adolescence.