Advanced Neuroimaging Evaluation of CNS Changes Associated With Efavirenz Therapy Switch to an Raltegravir-based Regimen
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
In this study investigators will use a multi-modal imaging approach of MRS and fMRI to
comprehensively assess the biological changes in the brain associated with EFV-based regimen
(EFV/FTC/TDF), specifically alterations in the brain circuitry, function and local
neurochemistry, and their correlation with neuropsychological function.