Advanced MRI Scan Before and After Radiation Therapy for the Detection of Intracranial Metastasis

• Status: Recruiting
• Trial end date: 2025-04-30
• Target enrollment: 0
• Participant gender: All

Summary

This clinical trial studies the different types of investigational imaging techniques called sequences during magnetic resonance imaging (MRI) of the head before and after radiation therapy in patients with cancer that has spread to the brain (intracranial metastases). This clinical trial also compares these new techniques with standard MRI imaging to see if sequences provide better images. Diagnostic procedures, such as MRI, may help find and diagnose solid organ cancer and find out how far the disease has spread.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: M.D. Anderson Cancer Center
• Collaborator: National Cancer Institute (NCI)
• Treatments: Chelating Agents

Criteria

Inclusion Criteria:

• An adult patient with pathology-proven solid organ cancer

• MRI of the brain with contrast, positive for at least one intra-axial metastatic lesion greater than 5 mm

• Planned treatment with stereotactic radiation

Exclusion Criteria:

• Contraindication to MR imaging

• Known allergy to gadolinium-based contrast agents

• Renal failure as defined by a glomerular filtration rate (GFR) less than 30 or the use of hemodialysis

• Pregnant

• Patients less than 18 years of age will be excluded