Overview

Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy

Status:
Terminated
Trial end date:
2020-04-21
Target enrollment:
Participant gender:
Summary
ALMERA is a randomized, phase II, open label study in patients with locally advanced non-small cell lung cancer (NSCLC) which will compare standard radiotherapy plus concurrent chemotherapy with or without consolidation versus the same treatment plus concurrent Metformin continuing for 12 months. Metformin is a well tolerated and inexpensive drug that has the potential to improve cancer patient outcomes.
Phase:
Phase 2
Details
Lead Sponsor:
Ontario Clinical Oncology Group (OCOG)
Collaborator:
Canadian Institutes of Health Research (CIHR)
Treatments:
Cisplatin
Metformin