Overview

Adrenal Insufficiency in Septic Shock

Status:
Terminated
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
Randomized controlled trial evaluating the duration of steroid replacement therapy in patients with adrenal insufficiency and septic shock. Patients will be randomized to receive either hydrocortisone 50 mg IV every six hours for seven days (control) or hydrocortisone 50 mg IV every six hours until 24 hours after achievement of hemodynamic stability (MAP > 65 mm Hg off of vasopressors).
Phase:
Phase 4
Details
Lead Sponsor:
The Methodist Hospital Research Institute
The Methodist Hospital System
Treatments:
Cortisol succinate
Epinephrine
Epinephryl borate
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Hydrocortisone hemisuccinate
Methylprednisolone
Prednisone
Racepinephrine