Overview

Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

Status:
ACTIVE_NOT_RECRUITING

Trial end date:
2028-12-01

Target enrollment:

Participant gender:

Summary

This is a pilot study in a small number of children and young adults with relapsed/progressive medulloblastoma (MB) looking at the feasibility and safety of adoptive cell therapy plus PD-1 blockade.

Phase:

PHASE1

Details

Lead Sponsor:

University of Florida

Collaborator:

Children's National Research Institute

Treatments:

Diphtheria-Tetanus Vaccine
Granulocyte-Macrophage Colony-Stimulating Factor
pembrolizumab