Administration of Ketamine to Prevent the Post-operative Pain

• Status: Completed
• Trial end date: 2005-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The surgery of breast cancer is responsible for post-operative pain, needing in about 30% some morphine consumption; like that, the association of ketamine with general anaesthesia may decrease morphine's use and so its adverse effects. The purpose is to evaluate the analgesic effect of a receptor NMDA's antagonist ( ketamine)

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Institut Bergonié
• Treatments: Ketamine

Criteria

Inclusion criteria:

• Patients 18 years older

• ASA class 1 or 2

• with surgery of breast cancer (mastectomy or tumorectomy)

Exclusion criteria:

.Kétamine hypersensitivity

• Major psychiatric disorders

• Major cardio-vascular disorders

• Major neurologic disorders

• Major ocular disorders

• Morphine in pre-operative period