Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock.

• Status: Completed
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the effects on systemic hemodynamics, microcirculation and organ function of human Protein C concentrate in patients with sepsis and septic shock.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Roma La Sapienza
• Treatments: Drotrecogin alfa activated; Protein C

Criteria

Inclusion Criteria:

• Severe sepsis or septic shock with plasma activity of protein C < 60 %

Exclusion Criteria:

• Pregnancy

• Risk of Bleeding

• Hemorragia

• age < 18