Overview

Administration of Clomiphene: Short and Long Term Metabolism in an Anti-Doping Setting

Status:
Completed
Trial end date:
2018-10-15
Target enrollment:
Participant gender:
Summary
Clomiphene (Clomid) is a drug FDA approved to treat female infertility, however, it is often used by men in an off-label setting to both treat male infertility and in a multitude of sports disciplines to increase performance. Study Objectives: - Determine detection windows for clomiphene and its metabolites in urine following a medium-term administration - Understand the effect of clomiphene administration on luteinizing hormone (LH), follicle-stimulating hormone (FSH), and serum testosterone (T) concentrations in a longitudinal manner - Identify changes in current steroidal module of Athlete Biological Passport
Phase:
Phase 1
Details
Lead Sponsor:
Stuart Willick
Collaborators:
Partnership for Clean Competition
Sports Medicine Research and Testing Laboratory
Treatments:
Clomiphene
Enclomiphene
Zuclomiphene