Adjuvant Docetaxel-Zoledronic Acid in High-risk Early Prostate Cancer Following Prostatectomy.
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Radical prostatectomy is used to treat early prostate cancer in otherwise well men, but is
followed by later cancer relapse in 1 in 4 cases. This study aims to see if post-operative
adjuvant therapy with a combination of zoledronic acid and docetaxel might help reduce
relapse in such cases. Patients will be randomized to receive the adjuvant combination
therapy or no therapy. All patients will be monitored closely for signs of relapse and
treated appropriately with conventional salvage therapy.