Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids

• Status: Terminated
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This research study helps to demonstrate that adding vitamins and fats (nutritional supplements) to a diet will help reduce body weight and improve the lipid profile. This will be done by examining the body weight and chemicals in the blood. The chemicals are the result of the brain using the fat that subjects eat in their diet. Some medications may also change the amount of these chemicals in a person's blood.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Augusta University
• Collaborators: Eli Lilly and Company; Medical Service Line ABRC; US Department of Veterans Affairs; VA Office of Research and Development
• Treatments: alpha-Tocopherol; Antioxidants; Olanzapine; Tocopherols; Tocotrienols; Vitamin E; Vitamins

Criteria

Inclusion Criteria:

• Age 18 to 55

• VA outpatient

• Diagnosis of schizophrenia by DSM-IV criteria

• Active treatment with olanzapine

• Medically healthy

Exclusion Criteria:

• Diagnosis of MR

• MMSE score of < 26

• Not on a stable dose of olanzapine