Adjunctive Steroid Combination in Ocular Trauma (ASCOT) Study
Status:
Completed
Trial end date:
2021-01-31
Target enrollment:
Participant gender:
Summary
Eye trauma is a leading cause of blindness and visual impairment. Penetrating injuries of the
eye are more likely to result in poor vision and the main cause of this is a scarring
response on the retina (proliferative vitreoretinopathy, PVR) The purpose of this study is to
investigate the potential of an anti-inflammatory treatment (triamcinolone acetonide) to
improve the outcome of surgery in eyes that have suffered severe trauma.There is good
evidence from laboratory studies that additional steroid treatment into and around the eye at
the time of surgery could reduce scarring by reducing inflammation and improve visual
outcomes.