Adjunctive Game Intervention for Anhedonia in MDD Patients

• Status: Not yet recruiting
• Trial end date: 2022-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a pilot study using game intervention as an adjuvant treatment, to evaluate the effect of the video game on anhedonia and associated functional change of brain in patients with depression. Participants will be randomized to Experimental group receiving a 8-week treatment of antidepressant drugs and game intervention, or Control group receiving a 8-week treatment of antidepressant drugs. Magnetic resonance imaging scanning and assessment of clinical characteristics and cognitive function were conducted before and after the intervention.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Central South University
• Treatments: Citalopram

Criteria

Inclusion Criteria:

• a diagnosis of Major Depressive Disorder according to DSM IV or V and validated via Mini International Neuropsychiatric Interview (M.I.N.I.)

• right handedness

• capability of understanding and finishing self-rating scales

• capability of providing informed consent

Exclusion Criteria:

• any other major psychiatric disorders following DSM-5 diagnostic criteria

• neurological diseases

• a history of drug abuse

• suicidal risk

• pregnancy

• any contraindication for brain MRI scan.