Overview

Adiponectin Polymorphisms, Insulin Resistance, and Pharmacokinetics in Obesity

Status:
Completed
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to determine the influence of insulin resistance on drug metabolism and response in obese subjects. The investigators hypothesize that expression of adiponectin (a hormone secreted by fat tissue), and specific variants in the adiponectin gene can predict the insulin resistance and drug response among obese subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Stanford University
Collaborator:
National Institute of General Medical Sciences (NIGMS)
Treatments:
Anesthetics
Fentanyl
Insulin
Propofol