This is a study of how well caregivers of children with malaria adhere to the recommended
regimen for lumefantrine-artemether (LA). Children were randomly assigned to either a group
receiving directly observed treatment in hospital or to a group treated at home by the
routine caregiver (typically, patient's mother). Clinical/parasitologic, hematologic,
pharmacologic and qualitative parameters were monitored over a 28-day follow-up period and
are used to evaluate drug adherence.
Details
Lead Sponsor:
Centers for Disease Control and Prevention
Collaborator:
Ifakara Health Research and Development Centre
Treatments:
Artemether Artemether-lumefantrine combination Artemether, Lumefantrine Drug Combination Artemisinins Lumefantrine